FIGURE 11.

KLF15 expression is reduced in HIV transgenic (Tg26) mice. Glomeruli were isolated, and RNA was extracted for real time PCR. A, KLF15 mRNA expression was measured in wild-type (WT) and Tg26 mice (n = 4, *, p < 0.05 versus control). B, Western blot analysis was performed in glomerular lysates from WT and Tg26 mice for KLF15 and GAPDH. The representative blot of three independent experiments is shown. The densitometry analysis of these blots is shown in the lower panel (n = 3, *, p < 0.01). C, representative images from the immunostaining of KLF15 in kidney sections from WT and Tg26 mice are shown.