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Stat3 siRNA inhibits G-CSF-induced Bv8 expression in bone marrow cells. Cells were transfected as indicated under “Experimental Procedures.” A and B, knockdown of Stat3 (A) or Stat5 (B) was assessed by Western blot. C, Bv8 expression was analyzed 48 h after siRNA transfection. Error bars represent S.E. Asterisk indicates significant difference between Stat3 siRNA and control siRNA treated groups (p < 0.05). Data shown are representative of three independent experiments.
