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WP1066 reduces the Bv8 increases in peripheral blood and bone marrow cells following in vivo administration of G-CSF. A and B, Bv8 concentrations by ELISA in plasma (A) and bone marrow cells (B). C, Bv8 expression in bone marrow cells. ELISA data were normalized to total protein concentrations. Error bars represent S.E. Asterisks indicate significant difference between WP1066- and vehicle-treated groups (p < 0.05).
