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Stat3 signaling is required for G-CSF-dependent Bv8 induction in human bone marrow cells. Human Bv8 expression by TaqMan in pooled human bone marrow cells after pretreatment with different concentrations of WP1066 for 1 h followed by incubation with 10 ng/ml human G-CSF for additional 4 h. Error bars represent S.E. Asterisk indicates significant difference between WP1066- and DMSO-treated groups (p < 0.05).
