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. 2012 Apr 19;287(23):19610–19621. doi: 10.1074/jbc.M112.344606

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© 2012 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 5. — The PBR is required for CdGAP to mediate cell rounding in fibroblast cells. A, COS-7 cells transfected with GFP, GFP-CdGAP(1–1425) or protein mutants were fixed 36 h after transfection and stained for actin with phalloidin-TRITC. Scale bar, 5 μm. B, quantification analysis of A. Cells counted as round had a nucleus covering more than 50% of the cell surface. These values represent an average of three independent experiments, with at least 100 cells counted per condition and per experiment; error bars, S.E. **, p < 0.001; *, p < 0.05 for the comparison to the control (GFP).