Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ubiquitination affects IFITM3 localization. HeLa cells were transfected overnight with empty vector or plasmids encoding the indicated IFITM3 constructs. Immunofluorescence with α-HA antibodies allowed IFITM3 visualization, and α-calreticulin staining allowed visualization of the ER. TOPRO-3 was used to visualize nuclei. Scale bars indicate 10 μm. UbΔ indicates mutation of Lys-24, Lys-83, Lys-88, and Lys-104 to alanine.
