. Author manuscript; available in PMC: 2013 Aug 1.

Published in final edited form as: NMR Biomed. 2012 Feb 14;25(8):993–999. doi: 10.1002/nbm.2762

Table 1.

Average apparent k_pl and k_pa rate constants with corresponding standard deviations in liver, kidney and vasculature ROIs from 5 animals. Conversion of labeled pyruvate to lactate increased in the liver after ethanol administration as seen by the increase in k_pl. There was no significant change in k_pl for kidney or vasculature, or in k_pa in any of the tissues. Though the inter-subject variability leads to relatively high standard deviations, the intra-subject comparison between pre-and post-ethanol in Fig. 5 clearly shows the change in rate constants.

	Liver k_pl (s⁻¹)	Liver k_pa (s⁻¹)	Kidney k_pl (s⁻¹)	Kidney k_pa (s⁻¹)	Liver vasc. k_pl (s⁻¹)	Liver vasc. k_pa (s⁻¹)	Kidney vasc. k_pl (s⁻¹)	Kidney vasc. k_pa (s⁻¹)
Pre-ethanol	0.049 ± 0.009	0.033 ± 0.007	0.018 ± 0.004	0.008 ± 0.003	0.004 ± 0.002	0.002 ± 0.001	0.008 ± 0.003	0.004 ± 0.002
Post-ethanol	0.064 ± 0.012	0.032 ± 0.007	0.019 ± 0.003	0.007 ± 0.003	0.004 ± 0.002	0.002 ± 0.001	0.007 ± 0.002	0.003 ± 0.001
Wilcoxon p-value	0.0431	0.8927	0.4982	0.5930	1.0000	0.1573	0.2850	0.1025