TABLE 1.

Interobserver agreement among all 6 observers

	Diagnostic category	Kappa value (95% confidence interval)
Morphology-only diagnosis	Not suspicious for STIC	0.51 (0.33–0.68)
	Suspicious for STIC	0.18 (0.08–0.30)
	Unequivocal for STIC	0.50 (0.35–0.66)
	Overall	0.39 (0.28–0.52)
p53 immunohistochemical score	Positive vs. negative	0.49 (0.28–0.67)
Ki-67 immunohistochemical score	Low vs. high	0.78 (0.65–0.91)
Final diagnosis	Normal/reactive	0.51 (0.32–0.68)
	p53 signature	0.51 (0.30–0.72)
	STIL	0.27 (0.14–0.42)
	STIC	0.67 (0.47–0.81)
	Overall	0.49 (0.39–0.62)

Key: STIC, Serous tubal intraepithelial carcinoma; STIL, serous tubal intraepithelial lesion.