Fig. 3. Representative dot plots (A) and mean frequencies (B) of IFN-γ producing γδ T cell subsets in ileum, spleen and blood of Gn pigs inoculated with HRV.
MNCs were cultured in vitro for 17 hours without antigen stimulation before staining for flow cytometry analysis. The right two dot plots in panel (A) show the representatives of IFN-γ producing CD2+CD8+ subset in ileum of Gn pigs infected with HRV at PID 3 or mock infected. Figures in panel (B) compare the mean frequencies of IFN-γ producing γδ T cells among the three subsets in ileum, spleen and blood of Gn pigs infected with HRV (PID 3 and PID 5) or mock infected (PID 0). Data are presented as mean frequency ± standard error of the mean (n = 4–7). Different capital letters on top of bars indicate significant differences in frequencies among the time points for the same γδ T cell subset and tissue (Kruskal-Wallis test, p < 0.05), while shared letters indicate no significant difference.