Table 2.
Activity of expiratory neurons in normoxia and hypoxia during sleep and wakefulness
| NREM
|
REM
|
Hypoxia if other than 10% | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Normoxia
|
Hypoxia
|
|
Normoxia
|
Hypoxia
|
|
|||||||
| Cell | Classification | η2 | Interspike interval (ms) | n | Interspike interval (ms) | n | Direction of Change | Interspike interval (ms) | n | Interspike interval (ms) | n | Direction of Change | |
|
|
|
|
|
|
|
|
|
||||||
| GWAY 37 | Edec | 0.7 | 104 (92) | 9356 | 112 (136)* | 6363 | ↑ | 124 (148) | 506 | ---- ---- | ---- | --- | |
| STA 57 | Edec | 0.7 | 124 (359) | 825 | 67 (173)* | 1713 | ↓ | ---- ---- | ---- | ---- ---- | ---- | --- | |
| STA 44 | Edec | 0.8 | 74 (169) | 1913 | 62 (95)* | 4279 | ↓ | 104 (227) | 3168 | ---- ---- | ---- | --- | 11% |
| STA 47*1 | Edec | 0.3 | 100 (198) | 1338 | 108 (252) | 1448 | nc | 548 (1373) | 704 | ---- ---- | ---- | --- | 11% |
| SUMA 74 | Edec | 0.1 | 173 (464) | 2840 | 400 (723)* | 217 | ↑ | 300 (464) | 123 | ---- ---- | ---- | --- | |
| SUMA 84*1 | Edec | 0.1 | 660 (2030) | 162 | 262 (481)* | 810 | ↓ | 6488 (14950) | 53 | ---- ---- | ---- | --- | |
| STA 42 | Eaug | 0.9 | 33 (128) | 7731 | 29 (96)* | 6465 | ↓ | 42 (136) | 10336 | ---- ---- | ---- | --- | |
| STA 45 | Eaug | 0.8 | 48 (156) | 1865 | 37 (123)* | 3076 | ↓ | 42 (112) | 9339 | ---- ---- | ---- | --- | |
| STA 56 | Eaug | 0.8 | 47 (111) | 1584 | 40 (101) | 997 | nc | ---- ---- | ---- | ---- ---- | ---- | --- | |
| GWAY 53 | Eaug | 0.7 | 40 (72) | 24041 | 32 (36)* | 10973 | ↓ | ---- ---- | ---- | ---- ---- | ---- | --- | |
| GWAY 20 | Eaug | 0.7 | 133 (289) | 1336 | 174 (420)* | 817 | ↑ | ---- ---- | ---- | 100 (287) | 1943 | --- | |
| GWAY 120 | Eaug | 0.7 | 96 (188) | 3914 | 64 (144)* | 3998 | ↓ | 100 (192) | 6602 | ---- ---- | ---- | --- | |
| STA 60 | Ethru | 0.9 | 49 (134) | 1073 | 34 (109)* | 1459 | ↓ | --- --- | --- | 29 (88) | 7829 | --- | |
| GWAY 128 | Ethru | 0.7 | 140 (280) | 2449 | 76 (192)* | 1339 | ↓ | 120 (268) | 2763 | --- --- | --- | --- | |
| STA 48 | Ethru | 0.6 | 47 (139) | 3651 | 44 (159) | 1957 | nc | 64 (200) | 4159 | --- --- | --- | --- | |
| ANGL 4a | LateE | 0.7 | 460 (889) | 257 | 229 (601)* | 169 | ↓ | ---- ---- | ---- | ---- ---- | ---- | --- | |
| GWAY 119a | LateE | 0.7 | 420 (896) | 1150 | 224 (936)* | 760 | ↓ | 484 (1720) | 1332 | ---- ---- | ---- | --- | |
| EDM 53 | LateE | 0.6 | 176 (295) | 2563 | 300 (457)* | 364 | ↑ | ---- ---- | ---- | 65 (72) | 10331 | --- | 13% |
| SUMA 55*1 | E cell | 0.2 | 156 (219) | 894 | 131 (294) | 735 | nc | --- --- | --- | --- --- | --- | --- | |
| DOLY 131a*1 | E cell | 0.1 | 92 (107) | 2697 | 28 (130)* | 437 | ↓ | ---- ---- | ---- | ---- ---- | ---- | --- | 12% |
| GWAY 111 | PS E-to-I | 0.2 | 248 (296) | 1091 | 164 (272)* | 2764 | ↓ | ---- ---- | ---- | ---- ---- | ---- | --- | 11% |
Data are means & (S.D.), n = # of spikes, arrows indicate significant increase or decrease in hypoxia value compared to normoxia, nc = no significant change,
*
p<0.05;
*1
neurons more active during wanning/apneic phase.