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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Menopause. 2012 Jun;19(6):650–657. doi: 10.1097/gme.0b013e31823df577

Table 5.

The ratio of ERLL/E2†

Ratio ERLL/E2 Higher E2, N=18 (SD) Lower E2, N=18 (SD)
DHEAS Group A 0.75 (0.09) 0.76 (0.09)
DHEAS Group B 0.74 (0.07) 0.72 (0.08)
DHEAS Group C 0.76 (0.08) 0.68 (0.08)
DHEAS Group D 0.64 (0.07) 0.49* (0.09)
†

This ratio provides a dimensionless estimate of the relative contribution of circulating E2 to the total estrogen receptor-alpha ligand load (ERLL) in serum samples segregated by the DHEAS concentrations. The highest concentrations of DHEAS are in Group A and the lowest are in Group D. The ratio for most groups is 0.7 or above indicating a relative constant contribution of non-E2 components in the estimate of ERLL. The ratio drops when DHEAS is low, indicating low Adiol, to 0.64 and 0.49 indicating a drop in non-E2 components. In the DHEAS Group D, lower E2 is significantly different when compared to the higher E2 (*p<0.05).