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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Pediatr Cardiol. 2012 Mar 9;33(5):683–688. doi: 10.1007/s00246-012-0180-4

Table 2.

Clinical profile in 4 patients treated with tadalafil as initial PDE-5i therapy

case age diagnosis 6MWD
(m)		 WHO
Functional
class		 TR velocity
(m/s)		 BNP
(pg/ml)		 mPAP
(mmHg)		 PVRI
(unitxm2)
before after before after before after before after before after before after
1 5 IPAH graphic file with name nihms-366203-t0002.jpg graphic file with name nihms-366203-t0003.jpg 3 2 4.5 3.2 1289 66 76 graphic file with name nihms-366203-t0004.jpg 16.7 graphic file with name nihms-366203-t0005.jpg
2 8 IPAH graphic file with name nihms-366203-t0006.jpg graphic file with name nihms-366203-t0007.jpg 3 1 3.6 2.9 163 124 58 graphic file with name nihms-366203-t0008.jpg 14.4 graphic file with name nihms-366203-t0009.jpg
3 8 IPAH 413 555 2 2 3.9 4.0 20 15 27 28 3.1 4.3
4 16 IPAH 581 652 2 2 3.9 3.1 46 15 38 graphic file with name nihms-366203-t0010.jpg 8.2 graphic file with name nihms-366203-t0011.jpg
Mean
+/−SD		 graphic file with name nihms-366203-t0012.jpg graphic file with name nihms-366203-t0013.jpg 497+/−
118.8		 603+/
−68.6		 2.5+/−
0.6		 1.5+/−
0.6		 4.0+/−
0.4		 3.3+/−
0.5		 380+/−
609.5		 55+/−
51.9		 50+/−
21.7		 28 11+/−
6.2		 4.3

BNP; brain natriuretic peptid, IPAH; idiopathic pulmonary arterial hypertension, mPAP; mean pulmonary arterial pressure, PDE-5i; phosphodiesterase type 5 inhibitors, PVRI; pulmonary vascular resistance index, TR; tricuspid regurgitation, WHO; World Health Organization, 6MWD; 6-minute walking distance