Table 6.
Multivariate linear regression showing relationship between Hemoglobin SS group, angiogenic growth factors, and WBC. Each angiogenic growth factor was strongly associated with the relationship between Hemoglobin SS and WBC. Significant reductions in the beta-coefficient (>25%) compared to the main exposure are marked with an asterisk (*).
| Intermediate outcome variable | ||
|---|---|---|
| Exposure variables | WBC | |
| β | Adj r 2 | |
| Group = Hb SS | 0.79 | 0.73 |
| Hb SS + Erythropoietin | 0.007 | 0.26 |
| Hb SS + Angiopoietin-2 | <0.001 | 0.17 |
| Hb SS + SDF-1α | 0.004 | 0.32 |