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Cell interactions in primordial follicles [3, 6]. Proposed cell interactions in the development of primordial follicles and the effect of the growth factors. Cell-cell interactions are mediated by tumor necrosis factor-alpha (TNFα), Kit ligand (KL), basic fibroblast growth (bFGF), leukemia inhibitory factor (LIF), bone morphogenetic protein-4 (BMP-4), keratinocyte growth factor (KGF), insulin, and anti-Mullerian hormone (AMH). With permission from M. Skinner.
