Table 2.
Oxidative stress parameters, cytokines, and acute-phase proteins in maternal and cord blood, in normal and PE cases.
| Maternal | UCB | |||||
|---|---|---|---|---|---|---|
| Normal (n = 42) | PE (n = 46) | P Value | Normal (n = 40) | PE (n = 42) | P Value | |
| Uric acid (mg/dL) | 4.2 ± 1.3 | 5.5 ± 1.6 | <0.001 | 4.5 ± 1.1 (n = 39) | 5.7 ± 1.6 (n = 40) | <0.001 |
| TAS (mmol/L) | 1.10 ± 0.22 | 1.07 ± 0.3 | 0.55 | 1.23 ± 0.27 (n = 39) | 1.17 ± 0.26 (n = 41) | 0.143 |
| TBARS (μmol/L) | 1.50 (1.29; 1.81) (n = 40) | 1.87 (1.49; 2.38) (n = 43) | 0.013 | 1.08 (0.95; 1.26) (n = 35) | 1.10 (0.85; 1.36) (n = 35) | 0.99 |
| TBARS/TAS | 1.48 (1.19; 1.66) (n = 40) | 1.76 (1.46; 2.13) (n = 43) | 0.003 | 0.93 (0.76; 1.31) (n = 35) | 0.93 (0.71; 1.25) (n = 35) | 0.84 |
| IL-6 (pg/mL) | 1.9 (1.2; 6.4) | 4.0 (2.3; 10.1) (n = 42) | 0.013 | 1.8 (1.2; 2.8) | 2.2 (1.5; 5.6) | 0.066 |
| TNF-α (pg/mL) | 1.2 (1.0; 1.6) | 1.9 (1.3; 2.4) (n = 43) | 0.001 | 1.9 (1.4; 2.4) | 1.8 (1.5; 2.1) | 0.34 |
| α1-Antitrypsin (mg/dL) | 191.6 ± 57.0 | 250.5 ± 74.9 | <0.001 | 120.2 ± 30.1 (n = 39) | 134.1 ± 23.5 (n = 40) | 0.025 |
| CRP (mg/L) | 3.1 (1.4; 5.8) | 4.1 (2.5; 7.9) | 0.033 | 0.03 (0.02; 0.04) (n = 39) | 0.04 (0.02; 0.08) | 0.011 |
n, number of cases; PE, Preeclampsia; UCB, umbilical cord blood.