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. 2012 May 22;2012:231586. doi: 10.1100/2012/231586

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Copyright © 2012 Mei-Fen Chen et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of LEM on plasma GOT and GPT levels in CCl₄-treated rats. (a) Changes of plasma GOT by oral administration of LEM in CCl₄-treated rats for 8 weeks. (b) Changes of plasma GPT by oral administration of LEM in CCl₄-treated rats for 8 weeks. Lane 1: vehicle-treated Wistar rats; lane 2: vehicle-treated CCl₄-induced rats; lane 3: silymarin- (200 mg/kg) treated CCl₄-induced rats; lane 4: LEM- (100 mg/kg) treated CCl₄-induced rats; lane 5: LEM- (200 mg/kg) treated CCl₄-induced rats; lane 6: LEM- (500 mg/kg) treated CCl₄-induced rats. Data represent mean ± SEM of eight animals. *P < 0.05, **P < 0.01, and ***P < 0.001 compared with CCl₄-induced group receiving vehicle.