Table 1.

The quantification of mRNA levels for Mn-SOD, Cu/Zn-SOD, GPx, or β-actin in liver isolated from CCl₄-induced rats receiving treatment with silymarin or LEM three times daily for 8 weeks. Quantification of mRNA levels using Mn-SOD/β-actin, Cu/Zn-SOD/β-actin, and GPx/β-actin was expressed as mean with standard error (SE) (n = 4 per group) in each group. *P < 0.05 compared with CCl₄-induced group receiving vehicle.

	Mn-SOD (arbitrary units) mRNA/β-actin	Cu/Zn-SOD (arbitrary units) mRNA/β-actin	GPx (arbitrary units) mRNA/β-actin
Control	1.31 ± 0.11*	1.20 ± 0.08*	1.91 ± 0.17*
CCl4	0.69 ± 0.06	0.75 ± 0.05	1.03 ± 0.08
+ Silymarin
200 mg/kg	1.15 ± 0.07*	1.37 ± 0.07*	1.48 ± 0.11*
+ LEM
100 mg/kg	0.64 ± 0.04	1.24 ± 0.09*	1.50 ± 0.18*
200 mg/kg	0.82 ± 0.05*	1.37 ± 0.11*	1.55 ± 0.13*
500 mg/kg	1.09 ± 0.08*	1.71 ± 0.13*	2.10 ± 0.15*