Table 2.
The quantification of protein levels for Mn-SOD, Cu/Zn-SOD, GPx, or actin in liver isolated from CCl4-induced rats receiving treatment with silymarin or LEM three times daily for 8 weeks. Quantification of protein levels using Mn-SOD/actin, Cu/Zn-SOD/actin, and GPx/actin was expressed as mean with standard error (SE) (n = 4 per group) in each group. *P < 0.05 compared with CCl4-induced group receiving vehicle.
| Mn-SOD (arbitrary units) protein/actin |
Cu/Zn-SOD (arbitrary units) protein/actin |
GPx (arbitrary units) protein/actin |
|
|---|---|---|---|
| Control | 1.24 ± 0.07* | 1.42 ± 0.15* | 1.18 ± 0.08* |
| CCl4 | 1.01 ± 0.04 | 1.02 ± 0.05 | 0.82 ± 0.06 |
| + Silymarin | |||
| 200 mg/kg | 1.16 ± 0.05* | 1.60 ± 0.09* | 1.11 ± 0.05* |
| + LEM | |||
| 100 mg/kg | 0.82 ± 0.06 | 0.91 ± 0.04 | 1.06 ± 0.05* |
| 200 mg/kg | 1.03 ± 0.11 | 1.07 ± 0.03 | 1.23 ± 0.14* |
| 500 mg/kg | 1.21 ± 0.10* | 1.67 ± 0.06* | 1.59 ± 0.17* |