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. Author manuscript; available in PMC: 2012 Jun 4.
Published in final edited form as: Lab Chip. 2011 Feb 3;11(6):1065–1073. doi: 10.1039/c0lc00472c

Figure 1.

Figure 1

A. Illustration of device design; each channel of the actual device is 10 pores wide and 200 pores long. B. Experimental images of ring-stage P. falciparum-infected (red arrows) and uninfected (blue arrows) RBCs in the channels at a pressure gradient of 0.24 Pa/µm. The small fluorescent dot inside the infected cell is the GFP-transfected parasite. At 8.3 s, it is clear that the uninfected cell moved about twice as far as each infected cell. C. The computational RBC model consists of 5000 particles connected with links. The P. falciparum parasite is modeled as a rigid sphere inside the cell. D. DPD simulation images of P. falciparum-infected RBCs traveling in channels of converging (left) and diverging (right) pore geometry at 0.48 Pa/µm.