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Structures and sequences of siRNAs and chiRNAs used in this study and their seed-matched target sequences. (A) The structures of 11 human class I siRNAs and six class II siRNAs. (B) The structures of 11 human class I chiRNAs and six class II chiRNAs. (C) The seed-matched target sequences used for psiCHECK-sm constructs shown in Figures 4 and 7. The red box indicates the seed region, and blue indicates the DNA-substituted regions within the chiRNA.
