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MAP was measured invasively in anesthetized male sGCα1–/–F2 mice homozygous for renin 1c (Ren1c/Ren1c = the B6 locus, n = 76), homozygous for renin 1d/renin 2 (Ren1d-Ren2/Ren1d-Ren2 = the S6 locus, n = 73), or heterozygous for both loci (Ren1c/Ren1d-Ren2; n = 135). *P < 0.001 versus all other groups by 1-way ANOVA.
