Table 2.
Antenatal and pregnancy-related complications reported among women delivering at Korle-Bu Teaching Hospital 2007–2008
| Complications | HbSS (N = 131) | HbSC (N = 112) | Comparison group (N = 717) |
|---|---|---|---|
| Hematologic | |||
| Anemia | 11 (8.4%)* | – | 20 (2.8%) |
| Sickle cell crisis | 12 (9.2%) | 7 (6.3%) | – |
| Infections | |||
| UTI | 2 (1.5%) | 2 (1.8%) | 6 (0.8%) |
| Cellulitis | – | – | 1 (0.1%) |
| Pyelonephritis | 1 (0.8%) | – | 1 (0.1%) |
| Pneumonia | 1 (0.8%) | – | 2 (0.3%) |
| Pregnancy-related complications | |||
| APH | 3 (2.3%) | 1 (0.9%) | 15 (2.1%) |
| Gestational diabetes | 1 (0.8%) | – | 7 (1.0%) |
| IUGR | 9 (6.9%)* | 2 (1.8%) | 14 (2.0%) |
| Eclampsia | 13 (9.9%)* | 6 (5.4%)‡ | 7 (1.0%) |
| Preeclampsia | 10 (7.6%)* | 7 (6.3%) | 20 (2.8%) |
| CPD | 6 (4.6%) | 1 (0.9%) | 22 (3.1%) |
| PIH | 23 (17.6%)*† | 4 (3.6%) | 19 (2.6%) |
| PROM | 18 (13.7%)*† | 5 (4.5%) | 15 (2.1%) |
| Placenta previa | 26 (19.8%)*† | 2 (1.8%) | 10 (1.4%) |
| Meconium staining | 1 (0.8%) | – | 8 (1.1%) |
Pearson Chi-square (χ2) test adjusting for Yates correction for continuity where appropriate were used to compare for statistical differences among the pregnant women. For instances in which there were too few subjects per cell for the Pearson χ2 test to be used, Fisher's exact test was used to compare discrete outcomes. Statistical significance was set at P ≤ 0.05. APH = antepartum hemorrhage; CPD = cephalopelvic disproportion; UTI = urinary tract infection; IUGR = intrauterine growth restriction; PIH = pregnancy-induced hypertension; PROM = premature rapture of membrane.
P < 0.0001 HbSS vs. Comparison.
P < 0.0001 HbSS vs. HbSC.
P < 0.001 HbSC vs. Comparison.