Table 4.
Maternal and perinatal outcomes at Korle-Bu Teaching Hospital 2007–2008
| Outcomes | HbSS | HbSC | Comparison group |
|---|---|---|---|
| No. of live births (n) | 115 | 100 | 669 |
| Gestational age* | |||
| Full-term birth | 85 (73.9%) | 78 (78.0%) | 485 (74.4%) |
| Preterm birth | 30 (26.1%) | 20 (20.0%) | 167 (25.6%) |
| Birth weight (kg)* | |||
| Mean ± SD | 3.0 ± 0.6 | 3.0 ± 0.7 | 3.0 ± 0.7 |
| < 2.5 | 14 (12.2%)† | 3 (3.0%)‡ | 92 (13.8%) |
| ≥ 2.5 | 89 (77.4%)† | 79 (79.0%)‡ | 525 (78.5%) |
| Fetal heart rate* | |||
| Mean ± SD | 130.1 ± 34.3 | 133.0 ± 31.7 | 135.0 ± 25.7 |
| Complication* | |||
| NICU | 29 (25.2%)§ | 16 (16.0%) | 100 (14.9%) |
| Grunting respiration | 3 (2.6%) | – | 8 (1.2%) |
| Asphyxia | 3 (2.6%) | 3 (3.0%) | 10 (1.5%) |
| Fetal distress | 11 (9.6%)§ | 3 (3.0%) | 17 (2.5%) |
| Mode of delivery* | |||
| Vaginal | 59 (51.3%)§ | 51 (51.0%)‡ | 448 (67.0%) |
| Cesarean | 56 (48.7%)§ | 49 (49.0%)‡ | 221 (33.0%) |
Pearson Chi-square (χ2) test adjusting for Yates correction for continuity where appropriate were used to compare for statistical differences among the pregnant women. For instances in which there were too few subjects per cell for the Pearson χ2 test to be used, Fisher's exact test was used to compare discrete outcomes. Statistical significance was set at P ≤ 0.05. NICU = neonatal intensive care unit; IUFD = intrauterine fetal death; SD = standard deviation.
*
Live births only.
†
P < 0.02 HbSS vs. HbSC.
‡
P < 0.001 HbSC vs. Comparison.
§
P < 0.001 HbSS vs. Comparison.