Table 1.
List of Abbreviations
| A1 and A3 ARs | A1 and A3 subtype adenosine receptors |
| AH | aqueous humor |
| AQP1 and AQP4 | aquaporin−1 and −4 water channels |
| BAF | bafilomycin A1 (inhibitor of vesicular ATP release) |
| bCE | bovine ciliary epithelial cell |
| CD73 | ecto-5′-nucleotidase |
| CE | ciliary epithelial cell |
| CFTR | cystic fibrosis transmembrane conductance regulator CI− channel |
| Cx | connexin hemichannel or gap junction |
| DTT | dithiothreitol (a reducing agent partially blocking PX1) |
| E-NPP1-3 | ecto-nucleotide pyrophosphatases/phosphodiesterases 1-3 |
| E-NTPD2, E-NTPD8 | ecto-nucleoside triphosphate diphosphohydrolases 2 and 8 |
| FGF | fibroblast growth factor |
| GM6001 | non-selective inhibitor of metalloproteinase activity |
| HCE | immortalized human nonpigmented ciliary epithelial cell |
| HEK293T | human embryonic kidney 293 cell line containing the SV40 large T-antigen |
| HEP | heptanol (relatively selective Cx inhibitor at 1 mM) |
| ICl,swell | swelling-activated CI− current |
| IOP | intraocular pressure |
| KN-62 | inhibitor of P2X7 |
| MMP | matrix metalloproteinase |
| NPE | nonpigmented ciliary epithelial cell or cell layer |
| P2X7 | P2X7 subtype ATP receptor |
| PX1 | pannexin-1 hemichannel |
| PE | pigmented ciliary epithelial cell or cell layer |
| PRO | probenecid (inhibitor of PX1 hemichannels) |
| Pxs | pannexins |
| RT-PCR | reverse-transcription polymerase chain reaction |
| TM | trabecular meshwork |
| TM5 | transformed human trabecular meshwork cell line |