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. Author manuscript; available in PMC: 2013 May 29.
Published in final edited form as: J Am Coll Cardiol. 2012 May 29;59(22):1979–1987. doi: 10.1016/j.jacc.2011.12.046

Figure 3. Effect of BRL on nNOS protein expression and the superoxide generation by acute nNOS inhibition.

Figure 3

(A) nNOS protein expression was significantly up-regulated by BRL treatment, though similar between sham and TAC. (B) Acute nNOS inhibition (striped bars) abrogated BRL-induced superoxide suppression in the presence of nNOS specific inhibitor Vinyl-L-NIO (L-VNIO, 100uM, 30 minutes in cold room), as compared with non-LVNIO treated samples (white bars). *P<0.01 vs. sham; †P<0.05 vs. TAC.