Table 3.

Major clinical signs that characterize patients with FOXG1 point mutations (in bold in the table)

	Girl (n = 11)a–d	Boy (n = 1)e
Head circumference at birth	2/11	1
Postnatal microcephaly <−3 SD	10/10 (1 N/A)	1
Eye contact and pursuit	4/7 (4 N/A)	1
Ability to walk	1/11	0
Hand stereotypies	11/11	1
Jerky-like movement	8/10 (1 N/A)	1
Bruxism	10/11	1
Seizure/epilepsy	7/10	0
Sleep disorders	5/10	1

N/A = Not available.

^aMencarelli et al. [2010].

^bAriani et al. [2008].

^cBahi-Buisson et al. [2010].

^dPhilippe et al. [2010].

^eLe Guen et al. [2011].