Table 3. Sensitivity of H5N1 influenza isolates to oseltamivir.
| Virus | Oseltamivir IC50* |
|---|---|
| H1N1 (H274)† | 0.69 |
| H1N1 (Y274)† | 85.92 |
| H3N2 (R292)‡ | 1.99 |
| H3N2 (K292)‡ | 1,600.00 |
| Hong Kong/483/97 | 4.86 |
| Hong Kong/213/03 | 5.07 |
| Vietnam /1194/04 | 2.49 |
| Vietnam/1203/04 | 7.68 |
| Chicken/VN/NCVD1/04 | 5.87 |
| Chicken/VN/NCVD8/03 | 9.90 |
*Median inhibitory concentration (IC50) of oseltamivir (nmol/L) for H5N1 influenza isolates and control H1N1 or H3N2 isolates (results for viruses shown are representatives of 31 isolates tested). †Wildtype (H274) and resistant mutant (Y274) influenza virus A/Texas/36/91 (H1N1). ‡Wildtype (R292) and resistant mutant (K292) influenza virus A/Victoria/3/75 (H3N2).