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. 2012 Mar 28;287(21):17140–17151. doi: 10.1074/jbc.M112.344093

FIGURE 3.

FIGURE 3.

Mn and in vitro blood-CSF barrier. A and B, impact of MnCl2 on the barrier integrity (TEERP) (A) and the capacitance (B) after basolateral MnCl2 incubation. Data, expressed as percentage of start value, represent mean values of at least three independent determinations with three replicates each with S.D. < ±10%. Mean TEERP and capacitance values of control cells were 801 ± 96 ohms*cm2 and 3.75*10−6 ± 2.09*10−7microfarads/cm2, respectively. C, phenol red concentration measured at 558 nm after 72-h basolateral MnCl2 incubation. Shown are mean values of least three independent determinations with three replicates ± S.D. (error bars). D, influence of MnCl2 on the TEERP values after apical MnCl2 incubation. Data, expressed as percentage of start value, represent mean values of at least three independent determinations with three replicates with S.D. < ±10%.