FIGURE 1.

Schematic representation of multisubunit organization for human B-family DNA polymerases. Subunits with similar functions are color-coded as follows: catalytic subunits are dark blue, B-subunits are red, and the C-subunit of Pol δ (p66) is green. For quick reference: in budding yeast, the catalytic subunits of Pol α, Pol δ, Pol ϵ, and Pol ζ are Pol1, Pol3, Pol2, and Rev3, respectively; the B-subunits of Pol α, Pol δ, and Pol ϵ are Pol12, Pol31, and Dpb2, respectively; and the C-subunit of Pol δ is Pol32.