Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A, schematic presentation of Rev3 protein and location of amino acid changes in its catalytic domain and CTD. B and C, effect of rev3 mutations on yeast survival and induced mutagenesis, respectively. Catalytically (Cat.) dead Rev3 has a double amino acid change (D1142A/D1144A) at the active site. Induced mutation frequencies (multiplied by 105) in the CAN1 gene were calculated by subtracting the spontaneous frequency from the corresponding frequencies after irradiation.
