Fenretinide reduces soleus and liver neutral lipid content.
A, DAG increased significantly with HFD versus SD, and FEN had no effect. B and C, in contrast, the increased TAG content in liver with HFD was significantly inhibited with FEN, suggesting a reversal of hepatic steatosis with FEN. *, p < 0.05 for treatment versus SD. +, p < 0.05 for HFD+FEN versus HFD (n = 6).