TABLE 3.

Levels of various endogenous compounds in enterocytes of WT and IE-Cpr-null mice

Enterocytes were isolated from male, age-matched (2–4-month-old) WT and IE-Cpr-null mice. The values presented are means ± S.D. (n ≥ 3).

Strain	Cholesterol (n = 3)	24-Dihydrolanosterol (n = 9)	FPP (n = 9)	GGPP (n = 9)	Heme (n = 3)	Bilirubin (n = 5)
	nmol/mg tissue	pmol/mg tissue	fmol/mg tissue	fmol/mg tissue	nmol/mg protein	fmol/mg tissue
WT	4.4 ± 0.6	NDa	209 ± 28	23 ± 5	3.3 ± 0.5	31.7 ± 18.3
IE-Cpr-null	4.0 ± 0.3	260 ± 18	260 ± 41b	39 ± 6c	3.6 ± 0.3	29.3 ± 5.2

^a ND, not detected; detection limit was ∼30 pmol/mg tissue.

^b p < 0.01, compared with WT value.

^c p < 0.001, compared with WT value.