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. 2012 Apr 5;287(21):17206–17213. doi: 10.1074/jbc.M111.304246

TABLE 1.

EAE induction with different rHuMOG preparations

Rats were immunized with 50 μg of the indicated rHuMOG preparation emulsified in complete Freund's adjuvant. Numbers are mean values (S.E.).

Immunization Disease incidence Day of disease onset Maximum disease score
rHuMOGPBS 0/15 0 (0)a
rHuMOGAC 3/6 28.3 (0.9)b 1 (0.5)c
rHuMOGREF 15/16 14 (1.6) 3.2 (0.3)

a p < 0.001 (Mann-Whitney Rank Sum test, rHuMOGPBS versus rHuMOGREF).

b p = 0.024 (Mann-Whitney Rank Sum test, rHuMOGAC versus rHuMOGREF).

c p = 0.006 (Mann-Whitney Rank Sum test, rHuMOGAC versus rHuMOGREF).