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. Author manuscript; available in PMC: 2012 Jun 4.
Published in final edited form as: Biochemistry. 2008 Jul 18;47(32):8456–8464. doi: 10.1021/bi8007643

Table 1.

Km (Mg•ATP) and Vmax (LTC4) Values of Wild-Type and Mutant MRP1s

Vmax (pmol mg−1 min−1)a Km (μM)a
MRP1 342.0 ± 50.3 61.0 ± 3.3
S1334T 618.3 ± 11.9 104.0 ± 8.3
a

Km (Mg•ATP) and Vmax (LTC4) values (n = 3) for wild type and S1334T were derived from the corresponding Michaelis–Menten curves shown in Figure 3. The P values for comparison of Vmax (LTC4) and Km (Mg•ATP) of wild type versus S1334T are 0.0016 and 0.0024.