Table 3.
Ordinary, marginal and multilevel logistic regression results: Odds ratios, OR, describing associations with 30-day mortality for patient-level and hospital-level characteristics
Risk factor | Ordinary | Marginal | Multilevel* | |||
---|---|---|---|---|---|---|
OR | 95% CI | OR | 95% CI | OR | 95% CI | |
Patient-level | ||||||
Age group (< 60 y, reference group): | ||||||
60-70 y | 1.5 | (1.2,2.0) | 1.5 | (1.2-1.8) | 1.5 | (1.2,2.0) |
70-80 y | 2.7 | (2.1,3.4) | 2.4 | (2.0-3.0) | 2.7 | (2.1,3.3) |
80+y | 3.6 | (2.8,4.8) | 3.3 | (2.7-4.5) | 3.7 | (2.8,4.9) |
Gender (female vs. male) | 1.3 | (1.1,1.6) | 1.3 | (1.1-1.5) | 1.3 | (1.1,1.6) |
NYHA Class (I&II, reference group): | ||||||
III | 1.3 | (1.1,1.6) | 1.3 | (1.1-1.6) | 1.4 | (1.1,1.6) |
IV | 1.7 | (1.4,2.1) | 1.6 | (1.3-2.0) | 1.7 | (1.4,2.2) |
Urgency of procedure (elective, reference group): | ||||||
Urgent | 2.0 | (1.6,2.4) | 1.8 | (1.5-2.2) | 2.0 | (1.6,2.4) |
Emergency/salvage | 5.4 | (4.3,7.0) | 4.9 | (4.0-6.0) | 5.5 | (4.3,7.0) |
Ejection fraction estimate (Mild, > 45%, reference group): | ||||||
Moderate (30-45%) | 1.4 | (1.2,1.8) | 1.3 | (3.0-1.6) | 1.4 | (1.2,1.8) |
Severe (< 30%) | 2.3 | (1.8,2.9) | 2.2 | (1.8-2.7) | 2.3 | (1.8,2.9) |
Hypercholesterolaemia | 1.0 | (0.8, 1.1) | 1.0 | (0.8-1.1) | 1.0 | (0.8,1.2) |
Preoperative dialysis | 2.2 | (1.5,3.2) | 2.2 | (1.5-3.0) | 2.2 | (1.5,3.2) |
Previous cardiac surgery | 1.6 | (1.3,2.0) | 1.6 | (1.3-2.0) | 1.7 | (1.3,2.0) |
Procedure type (CABG, reference group): | ||||||
Valve(s) | 1.7 | (1.3, 2.2) | 1.6 | (1.2-2.0) | 1.7 | (1.3, 2.2) |
Valve(s)+CABG | 2.2 | (1.8, 2.8) | 2.0 | (1.6-2.6) | 2.2 | (1.8, 2.8) |
Other | 3.4 | (2.7,4.1) | 3.0 | (2.4-3.7) | 3.4 | (2.8,4.2) |
Inotropic medication | 3.1 | (2.4,3.9) | 3.0 | (2.4-3.7) | 3.2 | (2.5,4.1) |
Peripheral vascular disease | 1.7 | (1.4,2.1) | 1.6 | (1.3-2.0) | 1.7 | (1.4,2.0) |
Body mass index (25+ vs. < 25 kg/m2) | 0.8 | (0.7,1.0) | 0.9 | (0.7-1.0) | 0.8 | (0.7,1.0) |
Hospital-level | ||||||
Academic affiliation (teaching vs. non-teaching) | 1.2 | (0.9,1.7) | 1.2 | (0.9-1.5) | 1.3 | (0.8,1.9) |
Median of the annual number of cardiac surgeries 2001-2009, per 100 surgeries | 0.88 | (0.83,0.94) | 0.93 | (0.9-1.0) | 0.91 | (0.82,1.1) |
*The estimated hospital-level variance, τ2, was 0.04.
*The estimated hospital-level variance, τ2, was 0.04