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. 2012 Jun 4;7(6):e38491. doi: 10.1371/journal.pone.0038491

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Singh et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Absolute number of human cells in lymph nodes, bone marrow and spleens of group 1 and group 7 mice. (B) Mesenteric and brachial lymph nodes from male mice obtained after 24 weeks of CD34⁺ cell transplantation in group 7 mice. (C) Flow cytometric analysis of engraftment percentage of CD3⁺ T cells and CD19⁺ B cells at 12 and 22 weeks after transplantation of CD34⁺ cells in representative mice from group 1 and group 7. (D) Flow cytometric analysis of CD4⁺CD8⁺, CD4⁺ and CD8⁺ population in thymus of 22 weeks engrafted mice. (E) Flow cytometric analysis of CD45RA⁺ and CD45RO⁺ positive CD3 cells 22 weeks after engraftment in mice from group 7. (F) Representative profile CD11c⁺ cells in spleen and CD14⁺ population in bone marrow and blood of group 7 mice 22 weeks after CD34⁺ cell transplantation.