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. 2012 Jun 4;7(6):e38284. doi: 10.1371/journal.pone.0038284

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Nabuurs et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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These graphs represent the blood half lives of tagged ^99mTc-ni3A and -pa2H (A), and untagged DTPA(¹¹¹In)-pa2H (B) in APP/PS1 mice and wildtype littermates. Data is shown as percentage of injected dose per gram of blood (%ID/g) over time. Based upon this plot the clearance is suggested to respectively consist of a fast and a slow phase, or only a single phase.