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. 2012 Jun 4;7(6):e38128. doi: 10.1371/journal.pone.0038128

Figure 1. Confirmation of the MSN manic phenotype using an experimental replication of the most robust behavioral measure from previous research on this mouse strain, total locomotor activity.

Figure 1

A) MSN mice display stable heightened locomotor activity relative the outbred strain. ***P<0.001. B) The probability density for MSN mouse total locomotor activity is bimodal, while the probability density for the control strain is unimodal. This leads us to the hypothesis that MSN mice may display behavioral bipolarism, a hypothesis that will be examined in future work.