Table 1. Correlations between CD4 count, peripheral HIV viral load and cervicovaginal HIV viral load with anti-HIV activity of cervicovaginal lavage from HIV-infected women.
Viruses tested for anti-HIV activity | CD4 count | Peripheral HIV viral load | Cervicovaginal lavage HIV viral load | |||||
Viral Tropism | Virus | N | Spearman ρ | P value | Spearman ρ | P value | Spearman ρ | P value |
R5 | BaL | 57 | 0.647 | <0.001 | −0.347 | 0.009 | −0.178 | 0.189 |
Yu2.c | 56 | 0.230 | 0.088 | −0.074 | 0.591 | 0.028 | 0.839 | |
X4 | IIIB | 57 | 0.549 | <0.001 | −0.313 | 0.019 | −0.134 | 0.326 |
NL4-3 | 45 | 0.120 | 0.433 | −0.262 | 0.085 | 0.251 | 0.101 | |
(T/F) | CH058.c | 51 | 0.245 | 0.083 | −0.033 | 0.823 | −0.052 | 0.718 |
Ch077.c | 56 | −0.087 | 0.523 | 0.059 | 0.670 | 0.153 | 0.266 | |
RHPA.c | 47 | 0.021 | 0.888 | −0.130 | 0.389 | 0.043 | 0.778 |
CVL levels of the laboratory-adapted HIV viruses IIIB and BaL correlated positively with CD4 count and negatively with the peripheral HIV viral load. By contrast, there were no significant correlations of CVL HIV viral load with anti-HIV activity against any virus.