Table 1. Summary of the characteristics of cells isolated from adult human SVZ/hippocampus.
Cell types | Proliferation | Sphere formation | Positive Markers | Differentiation |
Neurons | No | No | βIII-tubulin, MAP-2ab | N/A |
Astrocyte | No | No | GFAP | N/A |
Microglia | Limited ki67 | No | CD45, PU1, HLA-DR | N/A |
NPCs | Yes (BrdU, ki67) | Yes | Nestin, Sox-2, GFAP, Vimentin,PSA-NCAM, βIII-tubulin | βIII-tubulin, MAP-2ab, GFAP, Neurophysiology |
FbCs | Yes (BrdU, ki67 | Yes | Nestin, Sox-2, Vimentin, βIII-tubulin,Prolyl-4-hydroxylase, Fibronectin, S100A4,α-SMA, PDGFRβ | βIII-tubulin, Fibroblast, Fibronectin, No neurophysiology |
N/A = Not available due to negative results.