Table 2. Summary of the characteristics of brain-derived FbCs compared to the human lung-derived fibroblast cells.
Cell Lineage | Markers | Human Brain FbCs | Human Lung Fibroblasts |
MSCs | Thy1/CD90 | − | +++ |
5′-Nucleotidase/CD73 | + | +++ | |
Pericytes/Blood vessels | PDGFRβ/CD140β | ++ | ++ |
α-SMA | +++ | ++ | |
Nestin | ++ | ++ | |
Fibroblasts | Prolyl-4-hydroxylase α/β | +++ | +++ |
S100A4 | +++ | + | |
Vimentin | ++ | ++ | |
Fibronectin | +++ | +++ |
Arbitrary scale based on a combined observation of ICC, western blot and q-RT-PCR data.
− = not detected, + = small, ++ = medium, +++ = high expression.