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. 2012 May 2;32(18):6081–6091. doi: 10.1523/JNEUROSCI.6519-11.2012

Figure 6.

Figure 6.

Coapplication of low concentrations of CCH and DHPG induces a post-burst ADP. A, Individual responses to bursts of five APs in baseline condition (gray, t = 0 min in B) or after application (black, t = 15 min in B) of CCH (3 μm), DHPG (0.75 μm), or both (3 μm CCH + 0.75 μm DHPG). B, Time courses of the post-burst potential amplitudes after application of CCH, DHPG, or both. Gray-shaded area indicates period of drug application. C, Summary of the change in post-burst potentials (t = 15 min minus t = 0 min response) in each condition. In CCH groups: 3 μm, n = 12; 6 μm, n = 11. In DHPG groups: 0.75 μm, n = 15; 1.5 μm, n = 11. In CCH + DHPG group: 3 μm CCH + 0.75 μm DHPG; experiment (expt), n = 16. For the linear sum, 16 randomly selected pairs were used from the independent measures in 3 μm CCH and 0.75 μm DHPG. One-way ANOVA, p < 0.0001; post hoc tests versus experiment, **p < 0.001.