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The change in regional cerebral blood flow after ischemia-reperfusion.
| before MCAO | 10 min after MCAO | 10 min before reperfusion | 10 min after reperfusion | |
|---|---|---|---|---|
| WT | 100 | 13.8 ± 3.9** | 15.2 ± 3.9** | 123.5 ± 43.3 |
| MMP-9 KO | 100 | 12.9 ± 4.6** | 18.3 ± 5.4** | 116.6 ± 33.5 |
| MMP-2 KO | 100 | 12.5 ± 3.4** | 16.7 ± 5.1** | 107.9 ± 33.1 |
| dKO | 100 | 11.7 ± 5.2** | 13.4 ± 5.8** | 116.7 ± 49.0 |
dKO: MMP-2/9 double knockout. MCAO: middle cerebral artery occlusion.
p < 0.01 compared with the levels before MCAO.
