Table 2.
C57BL/6 | ||||||||||||||
Wks | Control | EE 0.01ppm | EE 0.1ppm | EE 1.3ppm | BPA 0.03ppm | BPA 0.3ppm | BPA 30ppm | |||||||
0 | 14.4 ± 0.6 | 14.1 ± 0.4 | 14.4 ± 0.4 | 14.7 ± 0.6 | 14.3 ± 0.8 | 13.7 ± 0.9 | 14.2 ± 0.9 | |||||||
1 | 15.5 ± 0.6 | 15.4 ± 0.9 | 14.0 ± 0.4 | 13.1 ± 0.4a | 16.1 ± 0.8 | 15.8 ± 0.6 | 16.4 ± 1.8 | |||||||
2 | 16.5 ± 0.6 | 15.7 ± 0.9 | 14.7 ± 0.9a | 13.2 ± 1.0a | 16.6 ± 0.7 | 16.1 ± 0.7 | 16.4 ± 0.6 | |||||||
3 | 17.5 ± 1.0 | 16.3 ± 1.3 | 14.6 ± 0.7a | 13.3 ± 0.7a | 17.8 ± 0.9 | 17.3 ± 0.4 | 17.2 ± 0.3 | |||||||
Status | gravida |
nulli gravida |
gravida |
nulli gravida |
gravida |
nulli gravida |
gravida |
nulli gravida |
gravida |
nulli gravida |
gravida |
nulli gravida |
gravid |
nulli gravida |
4 | 17.9 ± 0.9 | 17.1 ± 0.4 | 15.2 | 16.3 ± 1.1 | NA | 14.7 ± 0.8 | NA | 12.8 ± 0.9 | 18.2 ± 0.6 | 17.0 ± 0.5 | 17.7 ± 0.4 | 17.2 ± 0.6 | 17.6 ± 0.3 | 16.4 |
5 | 19.8 ± 1.1 | 19.0 ± 0.8 | 15.9 | 17.3 ± 1.5 | NA | 15.4 ± 0.4 | NA | 13.1 ± 1.5 | 19.9 ± 0.8 | 18.1 ± 1.2 | 19.7 ± 0.7 | 18.8 ± 0.0 | 19.7 ± 0.6 | 17.6 |
6 | 26.4 ± 1.7 | 20.4 ± 0.2 | 17.1 | 19.2 ± 0.6 | NA | 15.4 ± 1.1 | NA | 13.1 ± 0.6 | 25.5 ± 0.2 | 19.3 ± 0.1 | 26.6 ± 2.6 | 20.1 ± 0.1 | 26.7 ± 3.0 | 18.9 |
7 | 24.3 ± 0.8 | 21.2 ± 1.1 | 18.2 | 20.2 ± 2.0 | NA | 16.2 ± 0.6 | NA | 13.5 ± 1.3 | 32.3 ± 8.5 | 21.4 ± 0.2 | 27.8 ± 6.1 | 21.7 ± 1.2 | 26.3 ± 4.7 | 19.6 |
CD1 | ||||||||||||||
Wks | Control | EE 0.01ppm | EE 0.1ppm | EE 1.3ppm | BPA 0.03ppm | BPA 0.3ppm | BPA 30ppm | |||||||
0 | 20.1 ± 1.4 | 20.8 ± 0.6 | 19.9 ± 0.7 | 20.2 ± 1.7 | 20.3 ± 0.9 | 19.6 ± 1.3 | 19.3 ± 1.4 | |||||||
1 | 22.5 ± 1.2 | 24.0 ± 1.2 | 20.8 ± 1.7 | 18.6 ± 1.4a | 23.3 ± 1.0 | 23.4 ± 2.7 | 23.7 ± 1.6 | |||||||
2 | 24.6 ± 1.5 | 26.6 ± 1.8 | 21.8 ± 1.7 | 18.7 ± 1.3a | 25.4 ± 2.0 | 26.4 ± 4.2 | 27.0 ± 3.4 | |||||||
3 | 23.6 ± 1.0 | 25.0 ± 1.6 | 21.3 ± 1.3 | 18.3 ± 1.1a | 24.0 ± 1.8 | 25.5 ± 3.2 | 25.6 ± 2.3 | |||||||
Status | gravida |
nulli gravida |
gravida |
nulli gravida |
gravida |
nulli gravida |
gravida |
nulli gravida |
gravida |
nulli gravida |
gravida |
nulli gravida |
gravida |
nulli gravida |
4 | 26.0 ± 1.3 | NA | 27.9 ± 1.5 | 26.4 ± 2.0 | NA | 22.5 ± 1.2 | NA | 19.0 ± 1.4 | 25.2 ± 2.3 | 27.3 ± 2.6 | 27.4 ± 3.0 | 25.6 ± 2.8 | 26.8 ± 0.5 | 29.7 |
5 | 33.6 ± 2.4 | NA | 35.7 ± 6.2 | 31.2 ± 0.5 | NA | 23.0 ± 1.3 | NA | 19.3 ± 1.3 | 32.3 ± 5.1 | 29.0 ± 3.2 | 32.1 ± 1.3 | 26.5 ± 2.3 | 34.3 ± 1.9 | 29.6 |
6 | 53.4 ± 5.2 | NA | 33.7 ± 3.4 | 32.9 ± 3.5 | NA | 24.1 ± 2.4 | NA | 19.4 ± 1.4 | 47.6 ± 13.3 | 31.8 ± 4.2 | 45.6 ± 8.2 | 27.6 ± 3.2 | 33.7 ± 1.6 | 32.7 |
7 | 35.5 ± 2.7 | NA | 36.0 ± 0.8 | 32.2 | NA | 29.1 ± 1.9 | NA | 19.9 | 37.1 ± 1.6 | 34.8 ± 4.5 | 38.5 ± 1.0 | 38.5 ± 3.9 | 36.5 ± 2.8 | 37.9 |
Values represent group mean ± SD;
Significantly different from Control by one-way ANOVA (p < 0.05). Weeks 4–7 of treatment are separated by those F0 females that produced a live litter (Gravida) and those that did not produce a live litter (Nulligravida).