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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: J Allergy Clin Immunol. 2012 May 1;129(6):1579–1587.e1. doi: 10.1016/j.jaci.2012.04.009

Figure 3. OIT decreases gastrointestinal epithelial barrier function.

Figure 3

Mice were orally sensitized to OVA, followed by administration of egg white OIT on days 0–14. On day 15, segments of jejunum were removed and mounted in Ussing chambers. Transmural resistance was measured at baseline (left), and luminal to serosal transport of FITC-dextran was measured over a 90-minute period (right). **p<0.01.