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. 2012 Feb 22;40(11):4742–4753. doi: 10.1093/nar/gks151

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© The Author(s) 2012. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Mature and precursor sequences of miR-132 and miR-212 in human. (a) miR-132 and miR-212 share similar mature sequences; in red are indicated the diverging nucleotides between the two human sequences. (b) miR-132 and miR-212 mature sequences are highly conserved among vertebrates; in red are indicated the nucleotides diverging from the human sequence. (c) Sequences and predicted stem–loop structures of human pre-miR-132 and pre-miR-212. The mature miRNA sequences are indicated in red, the miRNA* sequences are indicated in grey and predicted hydrogen bounds are indicated in blue. This figure was designed using miRBase (http://www.mirbase.org) for miRNAs and pre-miRNAs sequences and the Vienna RNAfold webserver (http://rna.tbi.univie.ac.at/cgi-bin/RNAfold.cgi) for the prediction of the stem–loop structures.