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. 2012 Feb 22;40(11):5149–5161. doi: 10.1093/nar/gks163

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© The Author(s) 2012. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Crystal structures of _PfTrm14 and _TTCTrmN. (A and C) show the structure of _PfTrm14 in cartoon representation (A) and as a topology diagram (C); (B and D) show the structure of _TTCTrmN in cartoon representation (B) and as a topology diagram (D). β-strands are shown in red, yellow and blue for the core-THUMP, NFLD and RFM (sub)domains, respectively. α-Helices are shown in dark red, yellow and blue. The β-strand shared by the core-THUMP and NFLD subdomains is shown in orange. The two additional β-strands in the _PfTrm14 structure are named β_i and β_ii. The structure of _PfTrm14 contains sinefungin bound in the active site, represented in ball and stick.