Table 1. Characterization of the samples used in the gene profiling study.

Affection status	Sex	ID	AAE (years)	AAO (years)	Clinical/lifestyle characteristics	Geographic origina	Scan dateb
Control	F	1	68	—		Mirandela	A
	F	2	68	—	Hypertension	Mirandela	A
	F	3	73	—	Hypertension	Mirandela	B
	F	4	65	—	Hypertension, hypercholesterolemia	Mirandela	C
	F	5	73	—	Hypertension, hypercholesterolemia	Porto	C
	F	6	45	—		Mirandela	A
	F	7	48	—	Ever drinker	Mirandela	A
	F	8	47	—	Hypertension	Mirandela	A
	F	9	47	—	Hypertension, ever smoker	Porto	D
	F	10	48	—	Hypercholesterolemia, ever drinker	Lisboa	F
	M	11	69	—	Ever smoker, ever drinker	Vila Real	C
	M	12	72	—	Ever drinker	Vila Real	C
	M	13	66	—	Hypertension, hypercholesterolemia, ever smoker, ever drinker	Porto	F
	M	14	68	—	Hypercholesterolemia, ever drinker	Lisboa	F
	M	15	69	—		Lisboa	F
	M	16	45	—		Vila Real	F
	M	17	52	—	Hypertension, hypercholesterolemia, ever drinker	Vila Real	E
	M	18	53	—	Ever smoker	Vila Real	E
	M	19	48	—	Ever smoker	Lisboa	F
	M	20	50	—	Hypercholesterolemia, ever smoker, ever drinker	Lisboa	F
	Mean±s.d.		58.7±11.0
Case	F	21	71	65		Porto	F
	F	22	65	65	Hypertension	Vila Real	F
	F	23	73	70		Vila Real	B
	F	24	70	69	Hypertension, hypercholesterolemia	Vila Real	B
	F	25	65	65	Hypertension, hypercholesterolemia	Porto	F
	F	26	53	45	Hypertension, hypercholesterolemia, ever smoker, ever drinker	Porto	B
	F	27	54	49	Hypertension, diabetes, hypercholesterolemia, ever drinker	Vila Real	A
	F	28	47	43	Hypercholesterolemia	Vila Real	F
	F	29	54	50	Hypertension	Vila Real	A
	F	30	49	48	Diabetes, hypercholesterolemia, ever smoker, ever drinker	Porto	F
	M	31	69	65	Hypertension, diabetes, hypercholesterolemia, ever drinker	Mirandela	B
	M	32	74	72	Hypertension, ever drinker	Mirandela	C
	M	33	74	73	Hypertension, hypercholesterolemia, ever drinker	Mirandela	C
	M	34	68	66	Ever drinker	Mirandela	C
	M	35	71	65	Hypertension, ever smoker, ever drinker	Porto	C
	M	36	54	53	Diabetes, hypercholesterolemia, ever drinker	Mirandela	C
	M	37	52	48	Hypercholesterolemia, ever smoker, ever drinker	Mirandela	C
	M	38	46	45	Hypertension, ever drinker	Mirandela	B
	M	39	49	47	Ever smoker, ever drinker	Mirandela	B
	M	40	46	45	Hypertension, ever drinker	Vila Real	A
	Mean±s.d.		60.2±10.6	57.4±10.8

The principal demographic, clinical, and lifestyle characteristics of the study subjects are shown, including the geographic origin of the participants, the microarray hybridization group of the samples, and the mean values and s.d. of the age-at-examination (AAE) and age-at-onset (AAO), where applicable.

^aName of the city/town where the samples were collected.

^bThe microarrays of these samples were performed and scanned in six groups, coded here as A through F.