Figure 5. Inflammatory mediators are positively correlated with polyp progression in the ApcMin/+ mouse.

Correlations were performed between abundance of large polyps and mRNA expression of MCP-1 (A), IL-1β (B), IL-6 (C) and TNF-α (D) in section 3 of the intestines. All inflammatory mediators showed a positive relationship with abundance of large polyps (P<0.01).