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. 2005 Nov;11(11):1804–1806. doi: 10.3201/eid1111.050852

Table. Epidemiologic, clinical, and serologic information for 10 patients with African tick-bite fever*.

Patient Sex/age (y) Tick bite Delay before onset (d) Fever Headache Myalgia Eschar (site) Skin rash 1st serum† IgG/IgM 2nd serum† IgG/IgM Diagnosis
1 M/62 No 7 Yes No No Multiple (legs) No NA NA Probable
2 F/58 No 6 Yes No Yes Multiple (legs, arms) No 64/32 64/128 Confirmed
3 M/58 No 6 No Yes No Single (trunk) No 64/32 128/16 Confirmed
4 F/51 No 6 No Yes Yes Multiple (legs, trunk) No 0/64 128/16 Confirmed
5 M/58 No 5 Yes No Yes Multiple (legs) No 512/0 512/0 Confirmed
6 F/57 No 5 No No Yes Yes (unknown) Yes NA 32/16 Confirmed
7 M/65 No 5 Yes Yes Yes Multiple (hands) No 128/64 512/128 Confirmed
8 F/59 No 10 No No No Multiple (legs, arms, trunk) No 64/8 128/32 Confirmed
9 M/53 No 3 Yes Yes Yes Multiple (legs) Yes 0/0 1,024/512 Confirmed
10 M/51 No 8 Yes No Yes No Yes 32/32 64/64 Confirmed
Total (%) 0 60 40 70 90 30

*NA, not available; Ig, immunoglobulin; male-to-female ratio, 60%; mean age = 57.2 ± 4.5 years.
†Identical results obtained with both Rickettsia africae and R. conorii antigens.